Liverton, N.: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Preparation of 3-amino-1,4-benzodiazepin-2-ones via direct azidation with trisyl azide

John W. Butcher, Nigel J. Liverton, Harold G. Selnick, Jason M. Elliot, Garry R. Smith, Andrew J. Tebben, David A. Pribush, John S. Wai, David A. Claremon

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 177 KB

english, 1996

2

Identification and Characterization of 4-Methylbenzyl 4-[(Pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate, an Orally Bioavailable, Brain Penetrant NR2B Selective N-Methyl-d-Aspartate Receptor Antagonist

Libby, Brian E., Liverton, Nigel J., Bednar, Rodney A., Bednar, Bohumil, Butcher, John W., Claiborne, Christopher F., Claremon, David A., Cunningham, Michael, DiLella, Anthony G., Gaul, Stanley L.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 194 KB

english, 2007

3

Fractionated alkaline rare-metal granites: two examples

Timothy Liverton, Nilson F. Botelho

Journal:

Journal of Asian Earth Sciences

Year:

2001

Language:

english

File:

PDF, 876 KB

english, 2001

4

Plutonic rocks of the Thirtymile Range, Dorsey Terrane: ultrafractionated tin granites in the Yukon

Liverton, T., Alderton, D. H. M.

Journal:

Canadian Journal of Earth Sciences

Year:

1994

Language:

english

File:

PDF, 1.76 MB

english, 1994

5

ChemInform Abstract: Nonpeptide Glycoprotein IIb/IIIa Inhibitors: Substituted Quinazolinediones and Quinazolinones as Potent Fibrinogen Receptor Antagonists.

N. J. LIVERTON, D. J. ARMSTRONG, D. A. CLAREMON, D. C. REMY, J. J. BALDWIN, R. J. LYNCH, G. ZHANG, R. J. GOULD

Journal:

Year:

1998

File:

PDF, 38 KB

1998

6

ChemInform Abstract: An Efficient Synthesis of Tetrasubstituted Imidazoles from N-(2-Oxo)-amides.

Christopher F. Claiborne, Nigel J. Liverton, Kevin T. Nguyen

Journal:

Year:

1999

File:

PDF, 32 KB

1999

7

ChemInform Abstract: Design and Synthesis of Potent, Selective, and Orally Bioavailable Tetrasubstituted Imidazole Inhibitors of p38 Mitogen-Activated Protein Kinase.

Nigel J. Liverton, et al. et al.

Journal:

Year:

1999

File:

PDF, 32 KB

1999

8

ChemInform Abstract: Chemoselective Reactions of Amidines: Selective Formation of Iminopyrimidine Regioisomers.

John A. McCauley, Cory R. Theberge, Nigel J. Liverton

Journal:

Year:

2001

File:

PDF, 30 KB

2001

9

ChemInform Abstract: Pyridazine Based Inhibitors of p38 MAPK.

Charles J. McIntyre, Gerald S. Ponticello, Nigel J. Liverton, Stephen J. O'Keefe, Edward A. O'Neill, Margaret Pang, Cheryl D. Schwartz, David A. Claremon

Journal:

Year:

2002

File:

PDF, 35 KB

2002

10

Synthesis of the first sulfur-35-labeled hERG radioligand

Conrad E. Raab, John W. Butcher, Thomas M. Connolly, Jerzy Karczewski, Nathan X. Yu, Steven J. Staskiewicz, Nigel Liverton, Dennis C. Dean, David G. Melillo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 124 KB

english, 2006

11

Phosphorous acid analogs of novel P2–P4 macrocycles as inhibitors of HCV–NS3 protease

Marco Pompei, Maria Emilia Di Francesco, Uwe Koch, Nigel J. Liverton, Vincenzo Summa

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 763 KB

english, 2009

12

Kinetic characterization of novel NR2B antagonists using fluorescence detection of calcium flux

Bohumil Bednar, Michael E Cunningham, Laszlo Kiss, Gong Cheng, John A McCauley, Nigel J Liverton, Kenneth S Koblan

Journal:

Journal of Neuroscience Methods

Year:

2004

Language:

english

File:

PDF, 217 KB

english, 2004

13

An efficient synthesis of tetrasubstituted imidazoles from N-(2-Oxo)-amides

Christopher F. Claiborne, Nigel J. Liverton, Kevin T. Nguyen

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 154 KB

english, 1998

14

Pyridazine based inhibitors of p38 MAPK

Charles J McIntyre, Gerald S Ponticello, Nigel J Liverton, Stephen J O’Keefe, Edward A O’Neill, Margaret Pang, Cheryl D Schwartz, David A Claremon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 143 KB

english, 2002

15

Adenosine-2′-monophosphate derivatives: Structural requirements as substrates for inositol monophosphatase

Paul D. Leeson, Kim James, Ian C. Lennon, Nigel J. Liverton, Sue Aspley, Rosamond G. Jackson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 431 KB

english, 1993

16

Photochemical preparation of a pyridone containing tetracycle: A jak protein kinase inhibitor

James E. Thompson, Rose M. Cubbon, Richard T. Cummings, Linda S. Wicker, Robert Frankshun, Barry R. Cunningham, Patricia M. Cameron, Peter T. Meinke, Nigel Liverton, Youmin Weng, Julie A. DeMartino

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 136 KB

english, 2002

17

Novel 5-cyclopropyl-1,4-benzodiazepin-2-ones as potent and selective IKs-blocking class III antiarrhythmic agents

John W Butcher, Nigel J Liverton, David A Claremon, Roger M Freidinger, Nancy K Jurkiewicz, Joseph J Lynch, Joseph J Salata, Jixin Wang, Christine M Dieckhaus, Donald E Slaughter, Kamlesh Vyas

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 148 KB

english, 2003

18

Corrigendum to ‘Novel 5-Cyclopropyl-1,4-benzodiazepine-2-ones as Potent and Selective IKs-Blocking Class III Antiarrhythmic Agents’: [Bioorg. Med. Chem. Lett. 13 (2003) 1165]

John W Butcher, Nigel J Liverton, David A Claremon, Roger M Freidinger, Nancy K Jurkiewicz, Joseph J Lynch, Joseph J Salata, Jixin Wang, Christine M Dieckhaus, Donald E Slaughter, Kamlesh Vyas

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 65 KB

english, 2003

19

Nonpeptide glycoprotein IIb/IIIa inhibitors: Substituted quinazolinediones and quinazolinones as potent fibrinogen receptor antagonists

Nigel J. Liverton, Donna J. Armstrong, David A. Claremon, David C. Remy, John J. Baldvin, Robert J. Lynch, Guixiang Zhang, Robert J. Gould

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 209 KB

english, 1998

20

ChemInform Abstract: Preparation of 3-Amino-1,4-benzodiazepin-2-ones via Direct Azidation with Trisyl Azide.

J. W. BUTCHER, N. J. LIVERTON, H. G. SELNICK, J. M. ELLIOT, G. R. SMITH, A. J. TEBBEN, D. A. PRIBUSH, J. S. WAI, D. A. CLAREMON

Journal:

Year:

1996

File:

PDF, 34 KB

1996

21

Evaluation of MK-7009, A Novel Macrocyclic Inhibitor of NS3/4A Protease, in the Chimpanzee Model of Chronic Hepatitis C Virus Infection

S. Ludmerer, D. Graham, L. Handt, C. Fandozzi, C. Burlein, N. Liverton, J. McCauley, J. Vacca, D. Hazuda, S. Carroll, D. Olsen

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

22

MK-5172, a Novel Macrocyclic Inhibitor of NS3/4a Protease Demonstrates Efficacy Against Viral Resistance in the Chimpanzee Model of Chronic Hepatitis C Virus Infection

Steve Ludmerer, Steve Carroll, John McCauley, Mike Rudd, Paul Coleman, Nigel Liverton, Christine Burlein, Jill DiMuzio, Adam Gates, Don Graham, Carolyn McHale, Mark Stahlhut, Christine Fandozzi, Daria

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 64 KB

english, 2010

23

Creeping ahead

Liverton, John W.

Journal:

Manufacturing Engineer

Year:

1992

Language:

english

File:

PDF, 844 KB

english, 1992

24

[791] HCV ANTIVIRAL ACTIVITY AND RESISTANCE ANALYSIS IN CHRONICALLY INFECTED CHIMPANZEES TREATED WITH NS3/4A PROTEASE AND NS5B POLYMERASE INHIBITORS

D.B. Olsen, S.S. Carroll, L. Handt, S. Ludmerer, D. Graham, C. Fandozzi, J. DeLuca, N. Liverton, J. Vacca, D. Hazuda

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 151 KB

english, 2007

25

39 MK-5172: A NOVEL HCV NS3/4A PROTEASE INHIBITOR WITH POTENT ACTIVITY AGAINST KNOWN RESISTANCE MUTANTS

S. Carroll, J. McCauley, S. Ludmerer, S. Harper, V. Summa, M. Rowley, M. Rudd, P. Coleman, N. Liverton, J. Butcher, C. Mcintyre, J. Romano, K. Bush, M. Ferrara, B. Crescenzi, A. Petrocchi, M. Difilipp

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 47 KB

english, 2010

26

Discovery of triarylethanolamine inhibitors of the Kv1.5 potassium channel

Douglas C. Beshore, Nigel J. Liverton, Charles J. McIntyre, Christopher F. Claiborne, Brian Libby, J. Christopher Culberson, Joseph J. Salata, Christopher P. Regan, Joseph J. Lynch, Laszlo Kiss, Rober

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 407 KB

english, 2010

27

Development of macrocyclic inhibitors of HCV NS3/4A protease with cyclic constrained P2–P4 linkers

Rudd, Michael T., McIntyre, Charles J., Romano, Joseph J., Butcher, John W., Holloway, M. Katharine, Bush, Kimberly, Nguyen, Kevin T., Gilbert, Kevin F., Lyle, Terry A., Liverton, Nigel J., Wan, Bang-

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 2.24 MB

english, 2012

28

Molecular Modeling Based Approach to Potent P2−P4 Macrocyclic Inhibitors of Hepatitis C NS3/4A Protease

Liverton, Nigel J., Holloway, M. Katharine, McCauley, John A., Rudd, Michael T., Butcher, John W., Carroll, Steven S., DiMuzio, Jillian, Fandozzi, Christine, Gilbert, Kevin F., Mao, Shi-Shan, McIntyre

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 378 KB

english, 2008

29

Molecular Basis for p38 Protein Kinase Inhibitor Specificity

Lisnock, JeanMarie, Tebben, Andy, Frantz, Betsy, O'Neill, Edward A., Croft, Gist, O'Keefe, Stephen J., Li, Bing, Hacker, Candice, de Laszlo, Stephen, Smith, Anthony, Libby, Brian, Liverton, Nigel, Her

Journal:

Year:

1998

Language:

english

File:

PDF, 186 KB

english, 1998

30

Total synthesis of (+)-latrunculin A

Smith, Amos B., Noda, Ichio, Remiszewski, Stacy W., Liverton, Nigel J., Zibuck, Regina

Journal:

Journal of Organic Chemistry

Year:

1990

Language:

english

File:

PDF, 310 KB

english, 1990

31

Design and synthesis of 6?-substituted 2?,4?-dihydroxy-1?-phosphoryloxycyclohexanes, potent inhibitors of inositol monophosphatase

Baker, Raymond, Carrick, Carmel, Leeson, Paul D., Lennon, Ian C., Liverton, Nigel J.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1991

Language:

english

File:

PDF, 280 KB

english, 1991

32

MK-7009, a Potent and Selective Inhibitor of Hepatitis C Virus NS3/4A Protease

Liverton, N. J., Carroll, S. S., DiMuzio, J., Fandozzi, C., Graham, D. J., Hazuda, D., Holloway, M. K., Ludmerer, S. W., McCauley, J. A., McIntyre, C. J., Olsen, D. B., Rudd, M. T., Stahlhut, M., Vacc

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2010

Language:

english

File:

PDF, 429 KB

english, 2010

33

Total synthesis of (+)-jatropholones A and B. Exploitation of the high-pressure technique

Smith, Amos B., Liverton, Nigel J., Hrib, Nicholas J., Sivaramakrishnan, Hariharan., Winzenberg, Kevin.

Journal:

Journal of the American Chemical Society

Year:

1986

Language:

english

File:

PDF, 1.29 MB

english, 1986

34

Class III Antiarrhythmic Activity in Vivo by Selective Blockade of the Slowly Activating Cardiac Delayed Rectifier Potassium Current I Ks by ( R )-2-(2,4- Trifluoromethyl)- N -[2-oxo-5-phenyl- 1-(2,2,2-trifluoroethyl)-2,3-dihydro- 1 H -benzo[ e ][1,4]diazepin-3-yl]acetamide

Selnick, Harold G., Liverton, Nigel J., Baldwin, John J., Butcher, John W., Claremon, David A., Elliott, Jason M., Freidinger, Roger M., King, Stella A., Libby, Brian E., McIntyre, Charles J., Pribush

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 100 KB

english, 1997

35

Total synthesis of the latrunculins

Smith, Amos B., Leahy, James W., Noda, Ichio, Remiszewski, Stacy W., Liverton, Nigel J., Zibuck, Regina

Journal:

Journal of the American Chemical Society

Year:

1992

Language:

english

File:

PDF, 1.75 MB

english, 1992

36

Inhibitors of the Hepatitis C Virus NS3 Protease with Basic Amine Functionality at the P3-Amino Acid N-Terminus: Discovery and Optimization of a New Series of P2−P4 Macrocycles

Harper, Steven, Ferrara, Marco, Crescenzi, Benedetta, Pompei, Marco, Palumbi, Maria Cecilia, DiMuzio, Jillian M., Donghi, Monica, Fiore, Fabrizio, Koch, Uwe, Liverton, Nigel J., Pesci, Silvia, Petrocc

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 3.36 MB

english, 2009

37

General Photoisomerization Approach to trans-Benzobicyclo[5.1.0]octenes: Synthetic and Mechanistic Studies

Smith, Amos B., Wood, John L., Keenan, Terence P., Liverton, Nigel, Visnick, Melean

Journal:

Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 3.95 MB

english, 1994

38

Design and Synthesis of Potent, Selective, and Orally Bioavailable Tetrasubstituted Imidazole Inhibitors of p38 Mitogen-Activated Protein Kinase

Liverton, Nigel J., Butcher, John W., Claiborne, Christopher F., Claremon, David A., Libby, Brian E., Nguyen, Kevin T., Pitzenberger, Steven M., Selnick, Harold G., Smith, Garry R., Tebben, Andrew, Va

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 335 KB

english, 1999

39

An efficient photochemical approach to the trans-bicyclo[5.1.0]octene ring system

Wood, John L., Liverton, Nigel J., Visnick, Melean, Smith, Amos B.

Journal:

Journal of the American Chemical Society

Year:

1989

Language:

english

File:

PDF, 381 KB

english, 1989

40

Molecular Basis for p38 Protein Kinase Inhibitor Specificity

Lisnock, JeanMarie, Tebben, Andy, Frantz, Betsy, O'Neill, Edward A., Croft, Gist, O'Keefe, Stephen J., Li, Bing, Hacker, Candice, de Laszlo, Stephen, Smith, Anthony, Libby, Brian, Liverton, Nigel, Her

Journal:

Year:

1999

File:

PDF, 7 KB

1999

41

Correction. Total Synthesis of (+)-Latrunculin B

Zibuck, Regina., Liverton, Nigel J., Smith, Amos B.

Journal:

Journal of the American Chemical Society

Year:

1986

Language:

english

File:

PDF, 120 KB

english, 1986

42

Total synthesis of (+)-latrunculin B

Zibuck, Regina., Liverton, Nigel J., Smith, Amos B.

Journal:

Journal of the American Chemical Society

Year:

1986

Language:

english

File:

PDF, 384 KB

english, 1986

43

Total synthesis of (+)-jatropholone A and B

Smith, Amos B., Liverton, Nigel J., Hrib, Nicholas J., Sivaramakrishnan, Hariharan, Winzenberg, Kevin

Journal:

Journal of Organic Chemistry

Year:

1985

Language:

english

File:

PDF, 426 KB

english, 1985

44

Chemoselective Reactions of Amidines: Selective Formation of Iminopyrimidine Regioisomers

McCauley, John A., Theberge, Cory R., Liverton, Nigel J.

Journal:

Organic Letters

Year:

2000

Language:

english

File:

PDF, 41 KB

english, 2000

45

Synthesis of 2- and 6-deoxyinositol 1-phosphate and the role of the adjacent hydroxy groups in the mechanism of inositol monophosphatase

Baker, Raymond, Kulagowski, Janusz J., Billington, David C., Leeson, Paul D., Lennon, Ian C., Liverton, Nigel

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1989

Language:

english

File:

PDF, 340 KB

english, 1989

46

Identification of (1S)-phosphoryloxy-(2R,4S)-dihydroxycyclohexane as a potent inhibitor of inositol monophosphatase

Baker, Raymond, Leeson, Paul D., Liverton, Nigel J., Kulagowski, Janusz J.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1990

Language:

english

File:

PDF, 280 KB

english, 1990

47

Atrial Antifibrillatory Effects of Structurally Distinct IKur Blockers 3-[(Dimethylamino)methyl]-6-methoxy-2-methyl-4-phenylisoquinolin-1(2H)-one and 2-Phenyl-1,1-dipyridin-3-yl-2-pyrrolidin-1-yl-ethanol in Dogs with Underlying Heart Failure

Regan, C. P., Kiss, L., Stump, G. L., McIntyre, C. J., Beshore, D. C., Liverton, N. J., Dinsmore, C. J., Lynch, J. J.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2007

Language:

english

File:

PDF, 426 KB

english, 2007

48

Structure-dependent Impairment of Intracellular Apolipoprotein E4 Trafficking and Its Detrimental Effects Are Rescued by Small-molecule Structure Correctors

Brodbeck, J., McGuire, J., Liu, Z., Meyer-Franke, A., Balestra, M. E., Jeong, D.-e., Pleiss, M., McComas, C., Hess, F., Witter, D., Peterson, S., Childers, M., Goulet, M., Liverton, N., Hargreaves, R.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 3.49 MB

english, 2011

49

Sustained Viral Response in a Hepatitis C Virus-Infected Chimpanzee via a Combination of Direct-Acting Antiviral Agents

Olsen, D. B., Davies, M.-E., Handt, L., Koeplinger, K., Zhang, N. R., Ludmerer, S. W., Graham, D., Liverton, N., MacCoss, M., Hazuda, D., Carroll, S. S.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2011

Language:

english

File:

PDF, 102 KB

english, 2011

50

A Potent and Selective Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator Improves Movement in Rodent Models of Parkinson's Disease

Le Poul, E., Bolea, C., Girard, F., Poli, S., Charvin, D., Campo, B., Bortoli, J., Bessif, A., Luo, B., Koser, A. J., Hodge, L. M., Smith, K. M., DiLella, A. G., Liverton, N., Hess, F., Browne, S. E.,

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 299 KB

english, 2012